Herbal Treatment of Alzheimer Disease

Abstract

Alzheimer describes a syndrome of Alzheimer disease  it is a chronic neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons of substantia nigra pars compacta in the ventral midbrain.These processes are then responsible for the clinical features of Alzheimer  including bradykinesia, resting tremor, rigidity, and difficulty in initiating movements . The prevalence of  Alzheimer disease in industrialized countries is estimated at 0·5% of the general population and about 1.5% of the population older than age 60 years. People of all ethnic origins can be affected, and men are slightly more prone to the disorder. It described as paralysis agitans or shaking palsy, the term "A;lzheimer disease"Causes.The exact cause of disease is still a mystery, but many pathogenetic factors such as oxidative stress, free radical formation, mitochondria dysfunction, apoptosis, neuroinflammation, and genetic susceptibility  are critically involved in Alzheimer. Certain endogenous or exogenous toxins such as 6-hydroxydopamine and 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine, rotenone, Paraquat, Maneb, manganese, toluene, N- Hexane, carbonmonoxide, Mercury, Cyanide, Copper, Lead and Trichloroethylene, certain medications, viral infection, Alzheimer's disease, amyotrophic lateral sclerosis (ALS),  Alzheimer